Game Informer had a exclusive first look at Dead Space 2 which has quite a few changes in store.
Isaac, who now talks, will be on a space station called “Sprawl” which is much larger then the Ishimura. The space station has divded sectors which you will explore including residential areas and public spaces.
On the gameplay side Isaac will now be able to walk / jump in zero gravity along with being able to float and fly. While performing these new actions Isaac will be able to still use his weapons, so you aren’t entirely vunerable.
The multiplayer rumors were confirmed, but no details were announced.